Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology
نویسندگان
چکیده
منابع مشابه
Role of metalloproteinase matrix in development of cavity and diagnosis of pulmonary tuberculosis
Background: Matrix metalloproteases (MMPs) are multi-chain proteins that regulated by tissue inhibitor of metalloproteinases (TIMP) and several other mechanisms. This Includes transcription regulation and protein form secretion. The roles of MMPs in wound healing and tissue repair. In tuberculosis (TB), the activity of MMPs is increased and TIMP inhibitors decrease activity. Therefore, in tuber...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2018
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/jiy373